Exposure is divided into acute toxicity and chronic toxicity. Acute toxicity is exposure to poison over a short period, producing varying effects depending on the toxicity. A molecule with high toxicity will cause more adverse effects over a limited amount of exposure than a molecule with a lower toxicity however it will likely have a high rate of removal meaning that it cannot accumulate over time. In this case, the absorption process that takes place...
Exposure is divided into acute toxicity and chronic toxicity. Acute toxicity is exposure to poison over a short period, producing varying effects depending on the toxicity. A molecule with high toxicity will cause more adverse effects over a limited amount of exposure than a molecule with a lower toxicity however it will likely have a high rate of removal meaning that it cannot accumulate over time. In this case, the absorption process that takes place over the course of exposure will determine the dosage received by the organism and the effects it has. Chronic toxicity takes place over a long period and allows molecules of lower toxicity to accumulate over time and to produce adverse effects such as fluoride ions from sodium fluoride accumulating in the bone and causing disease. Accumulation can also take place in the lungs, where the water-insoluble particles become lodged. These particles can remain here, accumulating and causing harm to the preliminary cells or become absorbed by gastrointestinal absorption. This will take place because the particles bind to or become lodged within the mucus lining which is then transported using mucociliary transport to the pharynx where it can then be swallowed and taken to the stomach using peristalsis.
