Within the deep layers of the dermis are epidermal appendages. These are intradermal epithelial structures lined with epithelial cells (epithelial cells provide the barrier between internal cells and our environment) acting as the first point of defense against microbes. These cells have the potential for division and differentiation. These structures are vital as a source of epithelial cells, as they achieve the regeneration – ‘healing’ of injured or diseased tissue. This process is called ‘re-epithelialization.’...
Within the deep layers of the dermis are epidermal appendages. These are intradermal epithelial structures lined with epithelial cells (epithelial cells provide the barrier between internal cells and our environment) acting as the first point of defense against microbes. These cells have the potential for division and differentiation. These structures are vital as a source of epithelial cells, as they achieve the regeneration – ‘healing’ of injured or diseased tissue. This process is called ‘re-epithelialization.’ If the overlying epidermis is removed or destroyed in situations like partial thickness, burns abrasions, or split-thickness skin graft harvesting, then re-epithelialization will occur and is facilitated by fibroblasts.
