Can the impact of unmeasured confounders be excluded according to Bernstein’s study?

Asked on 03.12.2018 in All Questions.
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(Top Tutor) Studyfaq Tutor
As Bernstein’s study was observational, it is impossible to exclude the impact of unmeasured confounders. Lack of randomization in this cohort was a flaw. All participants were American, and the National Health and Nutrition Examination Survey (NHANES) revealed that Americans consume PM at more than three times the global average. Participants in Bernstein’s cohort may have an exaggerated exposure to PMs that represent one nationality, which is not a true representation of the global population, these results, therefore, lack generalisability. Streppel et al. highlight that food frequency questionnaires (FFQs) lack reproducibility. A limitation of this study was that dietary data were obtained from FFQ’s. FFQs’ with blank items at baseline for 70 men and ten women...
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