How does the damage of epidermis influence the xenobiotic absorption?

Asked on 08.10.2018 in All Questions.
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Substances may also be absorbed by trans-follicular absorption, with the xenobiotic bypasses the membrane barrier by diffusing around the hair stalk and into the hair follicle. Due to the presence of sweat glands in the epidermis absorption may take place here, however, the amount of absorption is proportional to the surface skin area covered by the sweat gland, approximately 0.1 to 1 per cent.  If the epidermis is damaged, then the dermis and the capillaries...
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