What factors affect the vasomotor reaction?

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Factors like the pre-existing vascular tone and local oxygen concentrations have a remarkable effect on the particular vasomotor reaction evoked by expanded astrocyte [Ca2+] I (43,50). In neurons, elevated [Ca2+]i initiates the synthesis of neuronal nitric oxide to produce nitric oxide (NO), as a consequence, NO leads to vasodilation through its activity on cGMP in arteriolar smooth muscle cells and has been proposed to regulate astrocyte-vascular signalling pathways by means of inactivation of EET and...
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