How does the iron influence the creation of cancer cells?

Asked on 07.01.2019 in All Questions.
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Studies suggest that iron promotes the formulation of reactive oxygen species or ROS from peroxidases through the Fenton reaction in the colon. It is this reaction and the production of hydroxyl radicals which is thought to contribute to the development of pro-mutagenic lesions and cellular toxicity. A study published in 2002 supports the previous statement, with results that identify an iron-overload induces oxidative damage to DNA causing breaks in the DNA strands and oxidized bases in the colon carcinoma cell line HT29 clone 19A, when ferric-nitrilotriacetate (a powerful hepatic tumor promoter) or hemoglobin, incubates the...
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