The practical application of GSLs induced pathogen resistance response in brassica will culminate in enhanced crop yield and preserve biodiversity. In plant breeding, the above techniques may be applied to propagate resistant varieties by exploiting individual and plant part based GSL concentration. Although, the signaling pathways involved in regulating GSL biosynthesis are unknown in some brassica crops, which merit further investigations to advance our understanding in this regard. According to Xu, more omics studies will elucidate how antimicrobial activities of GSL biosynthesis can be linked with the apoptotic stimulation of programmed cell death in major fungal pathogens. No doubt, this would provide insights on the development of...
The practical application of GSLs induced pathogen resistance response in brassica will culminate in enhanced crop yield and preserve biodiversity. In plant breeding, the above techniques may be applied to propagate resistant varieties by exploiting individual and plant part based GSL concentration. Although, the signaling pathways involved in regulating GSL biosynthesis are unknown in some brassica crops, which merit further investigations to advance our understanding in this regard. According to Xu, more omics studies will elucidate how antimicrobial activities of GSL biosynthesis can be linked with the apoptotic stimulation of programmed cell death in major fungal pathogens. No doubt, this would provide insights on the development of a new range of potent fungicides and fungal-based drugs. The GSL biosynthesis product, 4-methylsulfinylbutyl isothiocyanate (sulforaphane) does not only activate defense in naïve tissues but protect against virulent isolates. This suggests that GSL byproducts products are involved in cell-to-cell signaling and are prime bacteriostatic molecules albeit their applications warrant more in-depth studies. Furthermore, the findings of Zhang suggests that directly searching for resistance loci may not be the best approach at improving resistance in brassica to the necrotrophic pathogen; rather it may be necessary to have a broader perspective of the effects of resistance loci.
In future, the measuring of plant response to a pathogen using transcriptional approach is likely to be more available, which will permit the analysis of large-scale sizable expression data to achieving more robust results. In the meantime, the flourish of transcriptional data allows us to answer specific biological questions in the context of differential co-expression. For instance, the comparative analysis of differential co-expression during plant immune responses to different pathogens is an important topic. Differential co-expression analysis can boost the study of plant immune response-related transcriptomics and provide new insights into deciphering the molecular mechanisms of plant-pathogen interactions. More qualitative studies have the potential to give further insights into the synergistic effects of ROS and GSL metabolites given improving plant immunity.
