What are the processes that occur in the organism after drug consumption?
A drug reaches the market by the process of drug development. This consists of all the obstacles that a new drug must overcome so it can successfully go onto sales. This process includes the three mechanisms introduced by pharmacology. Throughout this paper, I’ll clarify the general aspects of drug development as well as its methods and techniques.
Pharmacokinetics, the processes that dictate the magnitude of plasma concentrations in response to a given dosage of a drug. Simplifying, pharmacokinetics can also be defined by what the body does to the drug. This mechanism incorporates four main processes known as absorption, distribution, metabolism and elimination or excretion, ADME. Sometimes, a fifth process known as toxicity is also considered, leaving the acronym as ADMET. The magnitude of the pharmacological effect of a drug depends on its concentrations at the site of action. Exemplifying, if the bioavailability of the drug, (the percentage of active drug substance absorbed and available to the target tissues), is 10%, that means that only 10% of the administered drug is available to get to its destine tissues.
Absorption, the movement of drug molecules from the site of entry to the circulation; the amount of absorption depends on the course of administration. The several routes of administration of a drug include, enteral, or oral; parenteral, or through an injection that can be subcutaneous, intramuscular, intravenous, intrathecal or epidural; pulmonary, through inhalation and nebulizers; and topical that includes through skin, eyes, ears and nasal mucosa.