What is the rate of absorption in the human body?
The rate of absorption is instead determined by pulmonary ventilation, cardiac output, the solubility of the xenobiotic in the blood and the solubility coefficient. The rate generally increases with physical activity which increases pulmonary ventilation and cardiac output while decreasing liver blood flow which consequently reduces the biotransformation rate. Biotransformation is the metabolic conversion of xenobiotics in the bloodstream such as ethanol. The general process for biotransformation sees lipid-soluble xenobiotics converted into large, water-soluble metabolites which can then be effectively excreted.