The stability of a molecule can also determine whether the molecule or the product molecule is poisonous to the molecule. For example tend to form peroxides such as hydrogen peroxide which also can decompose into hydroxyl radicals if enzymes such as catalyse, found in the liver do not have the chance to catalyse the breaking down of hydrogen peroxide into water and oxygen. Hydroxyl radicals react with lipids, polypeptides, proteins, and nucleic acids, especially thiamine...
The stability of a molecule can also determine whether the molecule or the product molecule is poisonous to the molecule. For example tend to form peroxides such as hydrogen peroxide which also can decompose into hydroxyl radicals if enzymes such as catalyse, found in the liver do not have the chance to catalyse the breaking down of hydrogen peroxide into water and oxygen. Hydroxyl radicals react with lipids, polypeptides, proteins, and nucleic acids, especially thiamine and guanosine. This can be incredibly harmful to the body, depending on the biological molecule affected. If the DNA is disrupted, in particular the stop codon, then this could lead to uncontrolled DNA replication and cell replication, forming a potentially deadly tumour. Furthermore the hydroxyl radical is an electrophile, a substance attracted to electron rich regions, meaning that unsaturated molecules, including nucleotide base pairs and amino acids, are at risk of electrophilic substitution, disrupting the function of the DNA and the proteins. The cell effected will affect the extent of the potential damage caused to rest of the organism, and the position of the nucleotide will affect what consequences will occur including the potential for cancer to develop.
